Dulcolax Contact Laxative Tablets - 200 Enteric Coated Tablets x 5 mg

Dulcolax Contact Laxative Tablets - 200 Enteric Coated Tablets x 5 mgDulcolax Contact Laxative Tablets - 200 Enteric Coated Tablets x 5 mg
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SGD $23.85
  • Product Code 9-556991-220299
  • EAN Code 9556991220299

Contact Laxative.

Bisacodyl 5 mg / tablet.

Properties:
Bisacodyl is a locally acting laxative from diphenylmethane derivatives group. As a contact laxative, for which also antiresorptive hydragogue effects have been descrided, bysacodyl stimulates, after hydrolysis in the large intestine, peristalsis of the colon and promotes accumulation of water and consequently electrolytes in the colonic lumen. This results in a stimulation of defecation, reduction of transit time, and softening of the stool.

Pharmacokinetics:
After administration of on oral solution or immediate release formulation of bisacodyl, the locally active laxative compound, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), is formed in the int6estine by hydrolysis of bisacodyl mainly by enzymes of the enteric mucosa. It can be absorbed, is conjugated and circulates in the blood stream in an inactive form (mainly as glucuronide) and is thenexcreted via the urine and bile. The majority of BHPM is excreted directly in the faeces.

DULCOLAX coated tablets are resistant to gastric and small intestinal juice, allowing release of the drug in the colon, the desired site of action. Bisacodyl is then hydrolyzed to the active component (BHPM) which is locally active without absorption. Consequently, this formulation has an onset of action between 6 -12 hours.

Indications:
For use of patients suffering from constipation.
For preparation of diagnostic procedures, in pre- and postoperative treatment and in conditions, which require defecation to be facilitated.

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